| Primary Identifier | MGI:7641512 | Allele Type | Targeted |
| Attribute String | Conditional ready | Gene | Dync1h1 |
| Transmission | Germline | Strain of Origin | C57BL/6NCrl |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Lysine codon 3334 (AAG) in exon 52 was changed to asparagine (AAT) (p.K3334N). A loxP site was inserted into intron 51 and an FRT site flanked neomycin resistance gene cassette and second loxP site were inserted into intron 52. Loss-of-function mutations in the human ortholog are associated with autosomal dominant axonal Charcot-Marie-Tooth type 20 disease (CMT20), autosomal dominant mental retardation 13 (MRD13) and autosomal dominant lower extremity-predominant spinal muscular atrophy 1 (SMALED1). |
