| Primary Identifier | MGI:7641518 | Allele Type | Endonuclease-mediated |
| Gene | Tet1 | Strain of Origin | C57BL/6J x DBA/2J |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Histidine codon 1652 (CAC) in exon 11 was changed to tyrosine (TAC) (p.H1652Y) and aspartic acid codon 1654 (GAC) was changed to alanine (GCC) (p.D1654A) using an sgRNA and an ssODN template with CRISPR/Cas9 technology. The mutations render the encoded peptide catalytically inactive. |
