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Allele : Igs2<em18(CAG-folA/cre)Smoc> intergenic site 2; endonuclease-mediated mutation 18, Shanghai Model Organisms Center
Primary Identifier  MGI:7626524 Allele Type  Endonuclease-mediated
Attribute String  Inducible, Recombinase Gene  Igs2
Inheritance Mode  Not Specified Strain of Origin  C57BL/6JSmoc
Induced With  trimethoprim Is Recombinase  true
Is Wild Type  false
molecularNote  CRISPR/cas9 endonuclease mediated genome editing is used to introduce P2A-trimethoprim(TMP)-inducible cre (ddCre) cassette immediately before the stop codon of Doc2b gene. Cre recombinase is fused to the destabilizing DHFR (or folA) domain, which can be transiently stabilized by the administration of TMP.
  • mutations:
  • Insertion
  • synonyms:
  • Igs2<em1(CAG-ddCre-V5-polyA)Smoc>,
  • Igs2<em1(CAG-ddCre-V5-polyA)Smoc>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

1 Driven By

2 Publication categories





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