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Allele : Klf1<em1(icre)Jbkr> Kruppel-like transcription factor 1 (erythroid); endonuclease-mediated mutation 1, James J Bieker

Primary Identifier  MGI:7616745 Allele Type  Endonuclease-mediated
Attribute String  Recombinase Gene  Klf1
Strain of Origin  C57BL/6J Is Recombinase  true
Is Wild Type  false
molecularNote  Using CRISPR technology, sgRNA (based on ATCTTTTGGGATACGGTCCT) was designed to insert a T2A self-cleaving peptide sequence, flanked by linkers, followed by a codon improved icre sequence into the C-terminal of the Klf1 gene fused in-frame to the final leucine amino acid.
  • mutations:
  • Insertion
  • synonyms:
  • EKLF-CRE,
  • EKLF-CRE
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

1 Driven By

2 Publication categories