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Allele : Mir137<tm1.2Ics> microRNA 137; targeted mutation 1.2, Mouse Clinical Institute

Primary Identifier  MGI:7616509 Allele Type  Targeted
Attribute String  Null/knockout Gene  Mir137
Transmission  Germline Strain of Origin  C57BL/6NTac
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site was inserted upstream and an FRT site flanked neomycin resistance gene cassette and second loxP site were inserted downstream. The neo cassette was removed through subsequent Flp-mediated recombination, leaving the locus floxed. The locus was deleted through subsequent Cre-mediated recombination. Mutations in the human ortholog are associated with intellectual disability, autism and schizophrenia.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Mir137<tm2.1Ics>,
  • Mir137<->,
  • Mir137<tm2.1Ics>,
  • Mir137<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

3 Publication categories