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Allele : Pkd2<tm1.1Witz> polycystin 2, transient receptor potential cation channel; targeted mutation 1.1, Ralph Witzgall
Primary Identifier  MGI:7642134 Allele Type  Targeted
Gene  Pkd2 Transmission  Germline
Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+> Is Recombinase  false
Is Wild Type  false
molecularNote  A mutated exon 8, floxed neomycin resistance cassette, mutated exon 9, wild-type exon 10, replaced exons 8-10. The neomycin resistance cassette was removed via cre-mediated recombination. Exons 8 and 9 encode the pore region and the mutations exchange the pore loop with that of the closely related cation channel polycystin-2L1.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • Pkd2<poreL1>,
  • Pkd2<poreL1>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories





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