| Primary Identifier | MGI:7643535 | Allele Type | Targeted |
| Gene | Gria2 | Transmission | Germline |
| Strain of Origin | 129S/SvEv-Gpi1<c> | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | Glutamine codon 607 (CAG) in exon 11 was changed to arginine (CGG) (p.Q607R) and a loxP site flanked neomycin resistance gene cassette was inserted into intron 11. The neo cassette was removed through subsequent Cre-mediated recombination. The mutation mimics the RNA editing at that codon from CAG to CIG, which is translated as a CGG codon, in the brain. |
