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Allele : Pcna<em1Gpc> proliferating cell nuclear antigen; endonuclease-mediated mutation 1, Gerry P Crossan
Primary Identifier  MGI:7643759 Allele Type  Endonuclease-mediated
Gene  Pcna Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
molecularNote  Lysine codon 164 (AAG) in exon 4 was changed to arginine (AGG) (p.K164R) using an sgRNA and an ssODN template with CRISPR/Cas9 technology. The mutation blocks monoubiquitination at the affected residue in the encoded peptide.
  • mutations:
  • Single point mutation
  • synonyms:
  • Pcna<K164R>,
  • Pcna<K164R>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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0 Driven By

2 Publication categories





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