Primary Identifier | MGI:7645651 | Allele Type | Endonuclease-mediated |
Gene | Senp2 | Strain of Origin | C57BL/6 |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Serine codon 343 (TCA) in exon 11 was changed to alanine (GCA) (p.S343A) using an sgRNA and an ssODN template with CRISPR/Cas9 technology. The mutation renders the affected residue unphosphorylatable in the encoded peptide. |