| Primary Identifier | MGI:7646871 | Allele Type | Endonuclease-mediated |
| Gene | Dnmt3l | Strain of Origin | (C57BL/6N x C3H/HeN)F1 x C57BL/6J |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Aspartic acid codon 124 (GAT) in exon 6 was changed to alanine (GCT) (p.D124A) using an sgRNA and an ssODN template with CRISPR/Cas9 technology. The mutation, in the ADD domain of the encoded peptide, reduces the affinity of the peptide to bind to H3K4me0. |
