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Allele : Pdcd1<em2(PDCD1)Cya> programmed cell death 1; endonuclease-mediated mutation 2, Cyagen Biosciences

Primary Identifier  MGI:7657308 Allele Type  Endonuclease-mediated
Attribute String  Inserted expressed sequence, Null/knockout Gene  Pdcd1
Inheritance Mode  Not Specified Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
molecularNote  The mouse Pdcd1 gene was edited using gene editing technology to replace the sequence encoding the extracellular domain of mouse PD-1 protein (aa.25~169) with the sequence from the human PD1 gene encoding the human PD-1 protein extracellular domain (aa.24~170) while retaining the mouse signal peptide.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Pdcd1<em1(hPDCD1)Cya>,
  • Pdcd1<em1(hPDCD1)Cya>
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

2 Publication categories