Primary Identifier | MGI:7657215 | Allele Type | Endonuclease-mediated |
Attribute String | Null/knockout | Gene | B2m |
Inheritance Mode | Not Specified | Strain of Origin | NOD.Cg-Prkdc<scid>/Cya |
Is Recombinase | false | Is Wild Type | false |
molecularNote | NKG B2m KO mice are constructed by knocking out the B2m gene on the background of NKG mice. Compared with NKG mice, NKG B2m KO mice have a significantly longer survival period after PBMC transplantation and can be used for long-term studies of PBMC immune system reconstitution. |