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Allele : Gars1<em3Gebai> glycyl-tRNA synthetase 1; endonuclease-mediated mutation 3, Ge Bai
Primary Identifier  MGI:7645902 Allele Type  Endonuclease-mediated
Gene  Gars1 Strain of Origin  C57BL/6
Is Recombinase  false Is Wild Type  false
molecularNote  Leucine codon 88 (CTC) in exon 2 was changed to alanine (GCC) (p.L88A) using an sgRNA and an ssODN template with CRISPR/Cas9 technology. The mutated residue is located in the WHEP domain of the encoded peptide.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • L42A-Gars<WT>,
  • L42A-Gars<WT>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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