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Allele : Lrsam1<em1Gebai> leucine rich repeat and sterile alpha motif containing 1; endonuclease-mediated mutation 1, Ge Bai
Primary Identifier  MGI:7645904 Allele Type  Endonuclease-mediated
Gene  Lrsam1 Strain of Origin  C57BL/6
Is Recombinase  false Is Wild Type  false
molecularNote  Cysteine codon 698 (TGC) in exon 25 was changed to tyrosine (TAC) (p.C698Y) using an sgRNA and an ssODN template with CRISPR/Cas9 technology. Mutations is the human ortholog are associated with Charcot-Marie-Tooth disease type 2P (CMT2P).
  • mutations:
  • Single point mutation
  • synonyms:
  • Lrsam1<C698Y>,
  • Lrsam1<C698Y>,
  • Lrsam1<CMT2P>,
  • Lrsam1<CMT2P>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

2 Publication categories





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