| Primary Identifier | MGI:7657258 | Allele Type | Endonuclease-mediated |
| Attribute String | Null/knockout | Gene | H2-Ab1 |
| Inheritance Mode | Not Specified | Strain of Origin | NOD.Cg-Prkdc<scid>/Cya |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | NKG-H2-Ab1 KO mice are generated by knocking out the H2-Ab1 gene on the background of NKG mice. Compared to NKG mice, NKG-H2-Ab1 KO mice can effectively reconstitute CD8+ T cells and exhibit improved survival after PBMC transplantation. They can be used for long-term studies on PBMC immune system reconstitution. |
