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Allele : H2-Ab1<em1Cya> histocompatibility 2, class II antigen A, beta 1; endonuclease-mediated mutation 1, Cyagen Biosciences
Primary Identifier  MGI:7657258 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  H2-Ab1
Inheritance Mode  Not Specified Strain of Origin  NOD.Cg-Prkdc<scid>/Cya
Is Recombinase  false Is Wild Type  false
molecularNote  NKG-H2-Ab1 KO mice are generated by knocking out the H2-Ab1 gene on the background of NKG mice. Compared to NKG mice, NKG-H2-Ab1 KO mice can effectively reconstitute CD8+ T cells and exhibit improved survival after PBMC transplantation. They can be used for long-term studies on PBMC immune system reconstitution.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • H2-Ab1<em1cya>,
  • H2-Ab1<em1cya>
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Trail: Allele

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0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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