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Allele : Ighmbp2<tm1(IGHMBP2)Cya> immunoglobulin mu DNA binding protein 2; targeted mutation 1, Cyagen Biosciences
Primary Identifier  MGI:7657266 Allele Type  Targeted
Attribute String  Inserted expressed sequence, Null/knockout Gene  Ighmbp2
Inheritance Mode  Not Specified Transmission  Germline
Strain of Origin  C57BL/6N Is Recombinase  false
Is Wild Type  false
molecularNote  Since there is an opposing gene upstream of the mouse Ighmbp2 gene, to avoid affecting the expression of the upstream gene, choose exon 5-15 as the humanized region. The exon 5-15 and flanking sequence of mouse Ighmbp2 was replaced with the entire human IGHMBP2 gene and ~10kb of human IGHMBP2 promoter, and the human sequence was inserted in reverse to prevent disruption of mouse Mrpl12 gene function.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Ighmbp2<tm1(hIGHMBP2)Cya>,
  • Ighmbp2<tm1(hIGHMBP2)Cya>
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele




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