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Allele : Dyrk1a<tm1.1Jdc> dual-specificity tyrosine phosphorylation regulated kinase 1a; targeted mutation 1.1, John D Crispino

Primary Identifier	MGI:7657948	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Dyrk1a
Transmission	Germline	Strain of Origin	C57BL/6NTac
Is Recombinase	false	Is Wild Type	false

molecularNote

A loxP site was inserted upstream of exon 5 and an FRT-flanked neomycin cassette and a loxP site was inserted downstream of exon 6. Cre-mediated recombination in the germline resulted in a deletion of the loxP flanked exon 5 and 6 sequences.

mutations:
Intragenic deletion

cellLines:
Not Specified

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

4 Publication categories

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