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Allele : Astn2<em2Hatn> astrotactin 2; endonuclease-mediated mutation 2, Mary E Hatten

Primary Identifier	MGI:7786605	Allele Type	Endonuclease-mediated
Attribute String	Null/knockout	Gene	Astn2
Strain of Origin	C57BL/6J	Is Recombinase	false
Is Wild Type	false

molecularNote

Using CRISPR/Cas9 methodologies ~3 kb of the promoter and exon 1, encoding the ATG start codon of the mouse Astn2 gene, was excised in C57BL/6J embryos.

mutations:
Intragenic deletion

synonyms:
Astn2<->,
Astn2<->

earliestPublication:
Hanzel M, et al. (2024) Mice lacking Astn2 have ASD-like behaviors and altered cerebellar circuit properties. Proc Natl Acad Sci U S A 121(34):e2405901121

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

2 Publication categories

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