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Allele : Phox2b<em3(cre)Heno> paired-like homeobox 2b; endonuclease-mediated mutation 3, Hideki Enomoto

Primary Identifier  MGI:7657398 Allele Type  Endonuclease-mediated
Attribute String  Recombinase Gene  Phox2b
Inheritance Mode  Not Specified Strain of Origin  Not Specified
Is Recombinase  true Is Wild Type  false
molecularNote  CRISPR/cas9 mediated recombination using guide RNAs and a donor vector inserted a cre/ERT2-ipA cassette into exon 1 around the first ATG of the gene. This was further modified by CRISPR/cas9 mediated recombination to insert a stop codon in the junction region between the cre and ERT2 sequences.
  • mutations:
  • Insertion
  • synonyms:
  • Phox2b<Cre>,
  • Phox2b<Cre>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

1 Driven By

3 Publication categories