| Primary Identifier | MGI:7786761 | Allele Type | Endonuclease-mediated |
| Attribute String | Inserted expressed sequence | Gene | Cftr |
| Strain of Origin | C57BL/6J | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | CRISPR/Cas9 genome editing technology was used to replace mouse exon 12 and flanking intronic sequences (130 bp upstream; 89 bp downstream) with the corresponding human sequence exon 12 containing the R553X mutation. |