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Allele : Cftr<em5Cwr> cystic fibrosis transmembrane conductance regulator; endonuclease-mediated mutation 5, Case Western Reserve University
Primary Identifier  MGI:7786762 Allele Type  Endonuclease-mediated
Gene  Cftr Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
molecularNote  CRISPR/Cas9 genome editing technology was used to introduce a G to A nucleotide alteration, changing the tryptophan at amino acid 1282 to a stop codon (W1282X).
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • Cftr<W1282X>,
  • Cftr<W1282X>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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0 Driven By

3 Publication categories





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