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Allele : Lrrk2<em1Yue> leucine-rich repeat kinase 2; endonuclease-mediated mutation 1, Zhenyu Yue

Primary Identifier  MGI:7737634 Allele Type  Endonuclease-mediated
Attribute String  Humanized sequence Gene  Lrrk2
Strain of Origin  C57BL/6J Is Recombinase  false
Is Wild Type  false
molecularNote  A missense mutation (nucleotide GAGTTT to GAATTC; conserved in both mouse and human) and a silent mutation creating an EcoRI site were introduced to exon 41 of the mouse Lrrk2 gene using CRISPR/cas9 methodologies.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • LRRK2<N2081D>,
  • LRRK2<N2081D>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

3 Publication categories