Primary Identifier | MGI:7737634 | Allele Type | Endonuclease-mediated |
Attribute String | Humanized sequence | Gene | Lrrk2 |
Strain of Origin | C57BL/6J | Is Recombinase | false |
Is Wild Type | false |
molecularNote | A missense mutation (nucleotide GAGTTT to GAATTC; conserved in both mouse and human) and a silent mutation creating an EcoRI site were introduced to exon 41 of the mouse Lrrk2 gene using CRISPR/cas9 methodologies. |