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Allele : Nr0b2<em1Jskk> nuclear receptor subfamily 0, group B, member 2; endonuclease-mediated mutation 1, Jongsook Kim Kemper
Primary Identifier  MGI:7707359 Allele Type  Endonuclease-mediated
Gene  Nr0b2 Strain of Origin  C57BL/6
Is Recombinase  false Is Wild Type  false
molecularNote  CRISPR/Cas9 technology introduced an ACC to GCA change resulting in a threonine to alanine substitution at amino acid 58 (p.T58A). Phosphorylation at Thr-58 is absent after treatment with FGF19.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • SHP-T58A,
  • SHP-T58A
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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0 Driven By

2 Publication categories





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