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Allele : Cep135<em2Mama> centrosomal protein 135; endonuclease-mediated mutation 2, Marcos Malumbres

Primary Identifier  MGI:7661141 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Cep135
Strain of Origin  (C57BL/6 x CBA)F2 Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR/Cas9 technology generated an 8 bp deletion in exon 2 between the ATG and TGA codons, generating a premature stop codon in exon 3. No detectable protein is seen at the centrosome in homozygous mouse embryonic fibroblasts.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Cep135<delta8>,
  • Cep135<delta8>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories