Primary Identifier | MGI:7661141 | Allele Type | Endonuclease-mediated |
Attribute String | Null/knockout | Gene | Cep135 |
Strain of Origin | (C57BL/6 x CBA)F2 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | CRISPR/Cas9 technology generated an 8 bp deletion in exon 2 between the ATG and TGA codons, generating a premature stop codon in exon 3. No detectable protein is seen at the centrosome in homozygous mouse embryonic fibroblasts. |