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Allele : Pten<tm1.1Ayr> phosphatase and tensin homolog; targeted mutation 1.1, Alexander Y Rudensky

Primary Identifier  MGI:7714642 Allele Type  Targeted
Attribute String  Reporter Gene  Pten
Transmission  Germline Strain of Origin  (129S6/SvEvTac x C57BL/6J)F1
Is Recombinase  false Is Wild Type  false
molecularNote  A furin cleavage linker-T2A-EYFP-FRT-PGK-Neomycin/Kanamycin-bGH pA-FRT cassette was inserted immediately upstream of the stop codon in exon 9 (the last exon) of the mouse Pten gene via homologous recombination. The FRT-flanked drug selection cassette was excised by crossing with R26 FLP mice.
  • mutations:
  • Insertion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele