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Allele : Sting1<tm1.1Ciphe> stimulator of interferon response cGAMP interactor 1; targeted mutation 1.1, Centre d'ImmunoPhenomique

Primary Identifier  MGI:7720866 Allele Type  Targeted
Attribute String  Conditional ready, Epitope tag Gene  Sting1
Transmission  Germline Strain of Origin  C57BL/6N
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site and an FRT-flanked neomycin resistance cassette were inserted in intron 2, 110 bp upstream of the start codon, a Twin-Strep-tag coding sequence (OST) was appended at the 5’ end of the first coding exon (exon 3), and a loxP site was inserted in intron 3, 40 bp downstream of the 3’ end of exon 3. Flp-mediated recombination removed the neomycin resistance cassette, leaving exon 3 floxed. The fusion of the OST to the protein can be used in affinity purification.
  • mutations:
  • Insertion
  • synonyms:
  • Tmem173<tm1Ciphe>,
  • STING-OST<fl>,
  • Tmem173<tm1Ciphe>,
  • STING-OST<fl>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories