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Allele : Rigi<tm1.1Ronz> RNA sensor RIG-I; targeted mutation 1.1, Rongbin Zhou

Primary Identifier	MGI:7715130	Allele Type	Targeted
Attribute String	Conditional ready	Gene	Rigi
Transmission	Germline	Strain of Origin	C57BL/6J
Is Recombinase	false	Is Wild Type	false

molecularNote

A loxP site was inserted upstream of exon 3 and an FRT-flanked neomycin resistance cassette and a second loxP site were inserted downstream of exon 3. The neomycin selection cassette was removed via cre-mediated recombination, leaving exon 3 floxed.

mutations:
Insertion

cellLines:
Not Specified

synonyms:
Ddx58<fl>,
Ddx58<fl>

earliestPublication:
Liu L, et al. (2019) Commensal viruses maintain intestinal intraepithelial lymphocytes via noncanonical RIG-I signaling. Nat Immunol 20(12):1681-1691

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

3 Publication categories

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