Primary Identifier | MGI:7712843 | Allele Type | Endonuclease-mediated |
Attribute String | Null/knockout | Gene | Mir582 |
Strain of Origin | Not Specified | Is Recombinase | false |
Is Wild Type | false |
molecularNote | CRISPR/Cas9 technology generated a 1,034 bp deletion by knocking-out Mir582 in the intron between exons 3 and 4 of the host gene Pde4d using sgRNAs 5'-CGTGCAGAGGACATATACACAGG and 5'-TGGTACACGGGATTAAGCTCAGG. While expression of Mir582 is absent in the brain, Pde4d expression is unaffected. |