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Allele : Kdm1a<tm1.1Ebg> lysine (K)-specific demethylase 1A; targeted mutation 1, Elena Battaglioli

Primary Identifier  MGI:7709217 Allele Type  Targeted
Attribute String  Modified isoform(s) Gene  Kdm1a
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A floxed neomycin resistance cassette replaced exon 8a, which is required for the neurospecific isoform. RT-PCR confirmed the lack of neurospecific isoform transcript in the hippocampus. The floxed neo cassette was subsequently removed via cre-mediated recombination in the germline, leaving a single loxP site in place of exon 8a.
  • mutations:
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories