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Allele : Gt(ROSA)26Sor<tm1(CAG-DICER1*G1809R)Mkur> gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Masahiko Kuroda
Primary Identifier  MGI:7709542 Allele Type  Targeted
Attribute String  Conditional ready, Humanized sequence, Inserted expressed sequence Gene  Gt(ROSA)26Sor
Transmission  Germline Strain of Origin  C57BL/6N
Is Recombinase  false Is Wild Type  false
molecularNote  A CAG promoter, loxP-flanked neomycin resistance gene, and human DICER1 with the p.G1809R mutation was inserted into the locus. The G1809R mutation is a missense mutation in the RNase IIIb domain that is frequently observed in patients with DICER1 syndrome.
  • mutations:
  • Insertion
  • synonyms:
  • DICER1<Mut>,
  • hDICER1<G1809R>,
  • DICER1<Mut>,
  • hDICER1<G1809R>
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

1 Driven By

3 Publication categories





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