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Allele : Slc5a7<em1Rbl> solute carrier family 5 (choline transporter), member 7; endonuclease-mediated mutation 1, Randy D Blakely

Primary Identifier  MGI:7709464 Allele Type  Endonuclease-mediated
Attribute String  Humanized sequence Gene  Slc5a7
Strain of Origin  C57BL/6J Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR/Cas9 technology generated an ATT to GTG change resulting in an isoleucine to valine substitution at amino acid 89 (p.I89V). In addition, a synonymous codon change in the adjacent codon, GGA to GGC, was also introduced to reduce chance of repeated CRISPR activity on the edited sequence.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • CHT<Val>,
  • CHT<Val>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

2 Publication categories