| Primary Identifier | MGI:7861782 | Allele Type | Endonuclease-mediated |
| Attribute String | Conditional ready, Humanized sequence | Gene | Trpv4 |
| Strain of Origin | C57BL/6J | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | A CRISPR/Cas9 generated mutation that results in the insertion of a loxP flanked cassette containing murine cDNA encoding exons 11-16 of Trpv4 into intron 10 of the endogenous gene. An arginine to histidine (R594H) missense mutation was also created in endogenous exon 11, downstream of the cDNA cassette. |
