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Allele : Rr590<em1Pike> regulatory region 590; endonuclease-mediated mutation 1, J Wesley Pike

Primary Identifier  MGI:7790911 Allele Type  Endonuclease-mediated
Attribute String  Modified regulatory region Gene  Rr590
Strain of Origin  C57BL/6 Is Recombinase  false
Is Wild Type  false
molecularNote  The Cyp27b1 enhancer, located in an Eef1akmt3 (Mettl21b) intron, was targeted using sgRNAs (equivalent to CCTACCTTCCCGCTACTGTTGGG and CCCTTCCTTAGGGACTTCATGGG) with CRISPR/Cas9 technology, resulting in a 5460 bp deletion (GRCm39:chr10:126868979-126874438) that includes the start of the coding last Eef1akmt3 exon.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • M21-IKO,
  • M21-IKO
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories