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Allele : Cbr1b<em1(IMPC)Ics> carbonyl reductase 1B; endonuclease-mediated mutation 1, Mouse Clinical Institute

Primary Identifier  MGI:7781817 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Cbr1b
Strain of Origin  C57BL/6N Is Recombinase  false
Is Wild Type  false
molecularNote  This allele was generated at the Institut Clinique de la Souris by electroporating Cas9 protein and 4 sgRNAs (equivalent to CCTCATCAAAGGGTTTGCA, AAGGAGATCAGGCCTTAAGC, TTACGGGGTAGGACTCCTT and TATTTGCAGGGTAGGTTACG), resulting in a 2814 bp deletion that includes the proximal promoter and exons 1 and 2 (ENSMUSE00000720738 and ENSMUSE00001039070; GRCm39), leading to the absence of protein.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Gm5678<em1(IMPC)Ics>,
  • Gm5678<em1(IMPC)Ics>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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0 Driven By

2 Publication categories

Trail: Allele