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Allele : Del(19Rbm4b-Rbm4)1Wtarn deletion, Chr 10, Yann Herault 1; deletion, Chr 19, Woan-Yuh Tarn 1
Primary Identifier  MGI:7666674 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Del(19Rbm4b-Rbm4)1Wtarn
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  Mice carrying Rbm4tm1Wtarn and Rbm4bem1Wtarn were crossed with an Tg(EIIa-cre)C5379Lmgd transgenic mouse line. Cre expression results in the excision of approximately 30 kb floxed region including 18.1kb of the intergenic region, Rbm4a (exons 2-4) and Rbm4b (exons 2-4) loci (containing predicted genes [Gm19103, Gm21992], regulatory regions [Rr358651, Rr360782, Rr360784] and the transcription start site region Tssr157511. This double knockout completely abolished Rbm4 and Rbm4b expression at both the mRNA and protein levels.
  • mutations:
  • Intergenic deletion
  • synonyms:
  • Rbm4dKO,
  • Rbm4dKO
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8 Mutation Involves

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