Primary Identifier | MGI:7781790 | Allele Type | Endonuclease-mediated |
Attribute String | Null/knockout | Gene | Paxbp1 |
Strain of Origin | C57BL/6N | Is Recombinase | false |
Is Wild Type | false |
molecularNote | This allele was generated at the Institut Clinique de la Souris by electroporating Cas9 protein and 4 sgRNAs (equivalent to TCAGTTCTTGAGAACCGCTC, GCAGACGTGTTAGCAAGATC, GTCGGCTGTCACGGGTGAAT and GCCGCTCAGTCGGCTGTCAC), resulting in a 292 bp deletion that includes exon 5 (ENSMUSE00001205218; GRCm39), leading to a frameshift and premature stop codon. |