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Allele : Paxbp1<em1(IMPC)Ics> PAX3 and PAX7 binding protein 1; endonuclease-mediated mutation 1, Mouse Clinical Institute

Primary Identifier  MGI:7781790 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Paxbp1
Strain of Origin  C57BL/6N Is Recombinase  false
Is Wild Type  false
molecularNote  This allele was generated at the Institut Clinique de la Souris by electroporating Cas9 protein and 4 sgRNAs (equivalent to TCAGTTCTTGAGAACCGCTC, GCAGACGTGTTAGCAAGATC, GTCGGCTGTCACGGGTGAAT and GCCGCTCAGTCGGCTGTCAC), resulting in a 292 bp deletion that includes exon 5 (ENSMUSE00001205218; GRCm39), leading to a frameshift and premature stop codon.
  • mutations:
  • Intragenic deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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2 Publication categories

Trail: Allele