Primary Identifier | MGI:7664593 | Allele Type | Endonuclease-mediated |
Attribute String | Modified regulatory region | Gene | Rr484 |
Strain of Origin | C57BL/6N | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The proximal Csn3 enhancer was deleted using sgRNAs (equivalent to CAGGTCATCCTATTGCCTCAAGG and GTGTAATGGTTCCCAGAAACAGG) with CRISPR/Cas9 technology, resulting in a 194 bp deletion. The deletion includes the GAS and GR motifs but not the NFIB motifs. |