| Primary Identifier | MGI:7738562 | Allele Type | Endonuclease-mediated |
| Attribute String | Conditional ready | Gene | Shank3 |
| Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | A loxP site upstream of exon 4 and a second loxP site upstream of exon 10 of the Shank3 gene flanking exons 4-9 and the third loxP site 5-kb downstream of exon 22 generated in Shank3tm2.1Yhj was targetted by CRISPR/cas9 methodologies to remove the second loxP site. Only two loxP sites flanking exons 4-22 of the Shank3 gene remain, one loxp between exon 3 and exon 4, and another loxp after exon 22. |
