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Allele : Tg(CAG-YAP1*)1Jfm transgene insertion 1, James F. Martin
Primary Identifier  MGI:7782579 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(CAG-YAP1*)1Jfm
Strain of Origin  FVB/N Is Recombinase  false
Is Wild Type  false
molecularNote  This transgene consists of a CAG promoter, a loxP-flanked eGFP-STOP cassette, a FLAG-tagged human YAP1 variant with eight serine (S) residues mutated to alanine (A) at the five canonical Lats-dependent phosphorylation motifs (YAP5SA, S61A, S109A, S127A, S128A, S131A, S163A, S164A, and S381A),and and IRES-LacZ reporter for lineage tracing. EGFP is expressed in embryonic and postnatal hearts before Cre recombination, and lacZ after recombination.
  • mutations:
  • Insertion
  • synonyms:
  • Tg[Jojo-Flag::YAP5SA]5JFM,
  • Tg[Jojo-Flag::YAP5SA]5JFM,
  • YAP5SA,
  • YAP5SA
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

1 Driven By

4 Publication categories





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