Primary Identifier | MGI:7782579 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(CAG-YAP1*)1Jfm |
Strain of Origin | FVB/N | Is Recombinase | false |
Is Wild Type | false |
molecularNote | This transgene consists of a CAG promoter, a loxP-flanked eGFP-STOP cassette, a FLAG-tagged human YAP1 variant with eight serine (S) residues mutated to alanine (A) at the five canonical Lats-dependent phosphorylation motifs (YAP5SA, S61A, S109A, S127A, S128A, S131A, S163A, S164A, and S381A),and and IRES-LacZ reporter for lineage tracing. EGFP is expressed in embryonic and postnatal hearts before Cre recombination, and lacZ after recombination. |