Primary Identifier | MGI:7738738 | Allele Type | Endonuclease-mediated |
Attribute String | Null/knockout | Gene | Tex44 |
Strain of Origin | C57BL/6N | Is Recombinase | false |
Is Wild Type | false |
molecularNote | CRISPR/Cas9 genome editing technology was used to generate a deletion of the complete open reading frame included in the unique exon of the gene. RT-PCR showed loss of Tex44 mRNA in testis samples from homozygous mutant males. Additional internal PCR performed on genomic DNA confirmed the complete absence of the gene. |