| Primary Identifier | MGI:7783477 | Allele Type | Endonuclease-mediated |
| Attribute String | Null/knockout | Gene | Arid3c |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Pronuclear injection of two Ultramers-loxP sequences, two Arid3c cRNAs and Cas9 targeting exon 2 generated the removal of exon 2 after non homologous end joining using CRISPR/Cas9 technology. The removal of exon 2 leads to a frameshift and generates a STOP codon, which causes a loss of 74% of the C-terminal part of the protein, including the ARID and REKLES domains. |
