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Allele : Zfp574<em1Btlr> zinc finger protein 574; endonuclease-mediated mutation 1, Bruce Beutler

Primary Identifier  MGI:7790452 Allele Type  Endonuclease-mediated
Attribute String  Hypomorph Gene  Zfp574
Strain of Origin  C57BL/6J Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR/Cas9 technology generated a T to A transversion resulting in a histidine to glutamine substitution at amino acid 512 (p.H512Q). The mutation recapitulates the ENU-induced glue allele and is a hypomorphic allele.
  • mutations:
  • Single point mutation
  • synonyms:
  • Zfp574<H512Q>,
  • Zfp574<H512Q>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

5 Carried By

0 Driven By

3 Publication categories