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Allele : Slc4a5<em1Brsk> solute carrier family 4, sodium bicarbonate cotransporter, member 5; endonuclease-mediated mutation 1, Botond Roska

Primary Identifier  MGI:7789054 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Slc4a5
Strain of Origin  (C57BL/6J x BALB/c)F2 Is Recombinase  false
Is Wild Type  false
molecularNote  Using CRISPR/Cas9 engineering, exon 3 of Slc4a5 (NM_001166067) was targeted with two antiparallel gRNAs to target the genomic sequence resulting in 201 bp insertion, 2 bp deletion and 7 bp insertion in exon 3 predicted to cause a premature stop codon before the first transmembrane regions.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Slc4a5<tm1>,
  • Slc4a5<tm1>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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0 Driven By

2 Publication categories

Trail: Allele