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Allele : Rr586<em1Iku> regulatory region 586; endonuclease-mediated mutation 1, Koichi Ikuta

Primary Identifier  MGI:7790518 Allele Type  Endonuclease-mediated
Attribute String  Modified regulatory region Gene  Rr586
Strain of Origin  C57BL/6 Is Recombinase  false
Is Wild Type  false
molecularNote  Il7r enhancer CNS9, containing a retinoic acid receptor-related orphan receptor (ROR)-responsive element (RORE), located in intron 2, was targeted using crRNAs, tracrRNA and an ssODN template with CRISPR/Cas9 technology, resulting in the mutation of the core binding site from AGGTC to CCGTG.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • CNS9-RORmut,
  • CNS9-RORmut
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

2 Publication categories