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Allele : Rad18<tm1b(EUCOMM)Wtsi> RAD18 E3 ubiquitin protein ligase; targeted mutation 1b, Wellcome Trust Sanger Institute

Primary Identifier  MGI:7763569 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Rad18
Transmission  Germline Strain of Origin  C57BL/6N
Is Recombinase  false Is Wild Type  false
Project Collection  EUCOMM
molecularNote  The L1L2_gt0 cassette was inserted at position 112670209 of Chromosome 6 upstream of the critical exon(s) (Build GRCm39). The cassette is composed of an FRT flanked lacZ/neomycin sequence followed by a loxP site. An additional loxP site is inserted downstream of the targeted exon(s) at position 112670934. The critical exon(s) is/are thus flanked by loxP sites. A null/knockout allele was created by cre recombinase expression in mice carrying the tm1a allele to remove the neo selection cassette and loxP-flanked critical exon(s). Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml
  • mutations:
  • Intragenic deletion
  • synonyms:
  • RD,
  • Rad18;delCre,
  • RD,
  • Rad18;delCre
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories