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Allele : Plod2<tm1.1Krako> procollagen lysine, 2-oxoglutarate 5-dioxygenase 2; targeted mutation 1.1, Deborah Krakow

Primary Identifier  MGI:7798735 Allele Type  Targeted
Attribute String  Modified isoform(s) Gene  Plod2
Transmission  Germline Strain of Origin  C57BL/6
Is Recombinase  false Is Wild Type  false
molecularNote  The targeting construct introduced an FRT-flanked neomycin resistance cassette with a 5' loxP site upstream of exon 13, a frameshift mutation into exon 13a, and a second loxP site downstream of exon 14. Flp-mediated recombination removed the selection cassette. This models a variant identified in two unrelated individuals with Bruck syndrome.
  • mutations:
  • Insertion
  • synonyms:
  • Plod2<fs>,
  • Plod2<fs>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

4 Publication categories