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Allele : Rr381<em11Kap> regulatory region 381; endonuclease-mediated mutation 11, Dietmar J. Kappes
Primary Identifier  MGI:7858951 Allele Type  Endonuclease-mediated
Attribute String  Modified regulatory region Gene  Rr381
Strain of Origin  C57BL/6J Is Recombinase  false
Is Wild Type  false
molecularNote  The Zbtb7b silencer, located upstream, was targeted with a dsODN template using TALEN technology (ZFN target sequences (capitalized) ACCGCTACCCTAACCcataaCTGGAAGGGGTTTAG), resulting in the mutation of one Ebox (T6) motif and three EGR (E6, E7, E9) and one NFAT (N5) binding sites.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • QK9<->,
  • QK9<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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2 Publication categories





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